East Prairie ZIP Codes — Mississippi County, MO

There is one unique ZIP code in East Prairie, Missouri and it is 63845. Area code: 573.

ZIP codes

188.60

sq mi land

6.59

sq mi water

573

area code

East Prairie, MO ZIP code map

About East Prairie, MO

East Prairie, Missouri, is a quaint city located in the southeastern part of the state. Known for its small-town charm, East Prairie offers a welcoming atmosphere with a tight-knit community. The city is characterized by its rural landscapes and friendly residents, making it a peaceful place to live and visit.

Location & geography

East Prairie is situated in Mississippi County, in the southeastern region of Missouri. It is bordered by several cities, including Charleston, which is approximately 10 miles to the west, and Sikeston, located about 17 miles to the northeast. The city's total land area spans 188.60 square miles, complemented by 6.59 square miles of water, contributing to a diverse terrain of fields and waterways.

Community & economy

The community of East Prairie is known for its strong agricultural roots, with industries such as farming playing a significant role in daily life. Residents enjoy the close-knit environment, where local events and gatherings foster a sense of belonging. Daily life in East Prairie is often punctuated by outdoor activities, family gatherings, and a shared appreciation for the town's natural beauty.

Transportation

East Prairie is accessible via several highways, including Highway 80 and Highway 61, which connect the city to larger urban centers. The nearest major airport is the Cape Girardeau Regional Airport, situated about 40 miles away, providing convenient travel options for residents and visitors. Public transportation options within the city are limited, emphasizing the need for personal vehicles for commuting.

History

Founded in the late 19th century, East Prairie has a rich history centered around agriculture and trade. Over the years, the city has witnessed the development of various industries, including retail and services, that contribute to its local economy. Notable events in the city's history include the establishment of community festivals that celebrate its heritage and bring residents together.

Did you know?

One surprising fact about East Prairie is that it is home to the East Prairie-Delta Area Chamber of Commerce, which plays a crucial role in promoting local businesses. Additionally, the city is known for its annual Christmas parade, which is a beloved tradition in the community.

ZIP codes for East Prairie, MO (1)

ZIP code	City	County	Map
63845	East Prairie	Mississippi	View map

Demographics & statistics

5,463

Population

40.7

Median age

$37,380

Median household income

$23,245

Per capita income

$90,100

Median home value

$742

Median monthly rent

59.2%

Home ownership

20.6%

Poverty rate

4.1%

Unemployment

1,696

Housing units

15.5%

Bachelor's or higher

Age distribution

Male Female

144

Under 5

152

116

5–9

122

282

10–14

298

171

15–19

181

126

20–24

132

336

25–34

355

287

35–44

302

362

45–54

382

128

55–59

136

142

60–64

149

344

65–74

363

158

75–84

166

85+

← Male

Female →

Age summary

Group	Count	%
Under 18	1,364	25.0%
18 and over	4,099	75.0%
65 and over	1,160	21.2%
Median age	40.7 years

Race & ethnicity

White 92.3%

Two or more races 3.9%

Hispanic or Latino 2.2%

Black or African American 1.4%

Asian 0.2%

Group	Count	%
White	5,155	92.3%
Two or more races	218	3.9%
Hispanic or Latino	125	2.2%
Black or African American	81	1.4%
Asian	9	0.2%

Household income

Under $10k 7.8%

$10k–$15k 9.2%

$15k–$25k 18.9%

$25k–$35k 9.9%

$35k–$50k 13.1%

$50k–$75k 13.7%

$75k–$100k 13.2%

$100k–$150k 11.4%

$150k–$200k 1.9%

$200k+ 0.8%

Range	% of households
Under $10k	7.8%
$10k–$15k	9.2%
$15k–$25k	18.9%
$25k–$35k	9.9%
$35k–$50k	13.1%
$50k–$75k	13.7%
$75k–$100k	13.2%
$100k–$150k	11.4%
$150k–$200k	1.9%
$200k+	0.8%
Median income	$37,380

Housing

Home values

Under $50k 29.0%

$50k–$100k 27.8%

$100k–$150k 15.9%

$150k–$200k 15.1%

$200k–$300k 8.6%

$300k–$500k 1.2%

$500k–$1M 2.5%

Housing overview

Metric	Value
Median home value	$90,100
Median rent / month	$742
Owner occupied	59.2%
Renter occupied	40.8%
Vacant	11.6%
Single-family detached	73.0%
Large apartment buildings	1.2%
Mobile homes	7.5%
Median rooms	5.3
Avg household size (owned)	2.33

Year built

Era	%
2020 or later	0.0%
2010–2019	6.5%
2000–2009	9.8%
1990–1999	8.1%
1980–1989	15.3%
1970–1979	19.9%
1960–1969	19.0%
1950–1959	7.5%
1940–1949	8.2%
1939 or earlier	5.7%

Bedrooms

Size	% of units
No bedroom (studio)	0.0%
1 bedroom	5.7%
2 bedrooms	33.4%
3 bedrooms	49.9%
4 bedrooms	10.1%
5+ bedrooms	0.9%

Vehicles per household

Vehicles	% of households
No vehicle	16.1%
1 vehicle	37.2%
2 vehicles	22.1%
3 or more	24.5%

Heating fuel

Fuel type	%
Utility gas	47.3%
Electricity	43.5%
Propane / LP gas	7.3%
Wood	0.6%
Solar	0.3%

Households & families

Household type	Count	%
Married-couple family	1,036	44.2%
Cohabiting couple	180	7.7%
Male householder, no spouse	375	16.0%
Female householder, no spouse	753	32.1%
Households with children under 18	824	35.2%
Households with seniors (65+)	876	37.4%
Average household size	2.31

Marital status

Status	Male	Female
Never married	29.2%	15.3%
Married	49.4%	48.3%
Separated	3.6%	3.2%
Widowed	1.4%	12.5%
Divorced	16.3%	20.7%

Education

Less than 9th grade 5.1%

Some HS, no diploma 17.2%

HS graduate 44.5%

Some college, no degree 14.7%

Associate's degree 3.1%

Bachelor's degree 9.6%

Graduate / professional 5.9%

Metric	%
HS diploma or higher	77.7%
Bachelor's or higher	15.5%

School enrollment (ages 3–17)

Type	Count	%
Nursery / preschool	56	4.5%
Kindergarten	43	3.5%
Elementary school	708	57.2%
High school	301	24.3%
College / grad school	129	10.4%

Employment

Industry of employment

Education & healthcare 24.7%

Retail trade 14.2%

Agriculture & mining 13.3%

Arts, food & hospitality 10.7%

Manufacturing 9.6%

Construction 6.8%

Public administration 5.9%

Transportation & utilities 5.8%

Professional & management 4.2%

Wholesale trade 3.0%

Information 0.7%

Finance & real estate 0.7%

Other services 0.4%

Occupation

Category	%
Management, business & arts	28.9%
Service	15.5%
Sales & office	19.6%
Natural resources & construction	18.0%
Production & transportation	18.0%

Employment type

Type	%
Private sector	77.0%
Government	15.5%
Self-employed	7.4%
Unpaid family workers	0.1%

Commute

Method	%
Drive alone	81.0%
Carpool	11.9%
Public transit	0.1%
Walk	2.9%
Other means	0.9%
Avg commute (minutes)	19.6

Poverty

All people 20.6%

Under 18 years 16.2%

18 and over 22.0%

Married-couple families 6.9%

Female-led households 46.9%

Income support

Source	% of households
Social Security	47.4%
Retirement income	17.6%
Supplemental Security	15.6%
Cash public assistance	4.3%
Food stamps / SNAP	31.6%

Health indicators

Condition	%
High blood pressure	37.6%
High cholesterol	36.7%
Heart disease	9.7%
Stroke	5.0%
Asthma	11.3%
Arthritis	34.9%
Kidney disease	4.1%
Pulmonary disease	13.7%
Cancer	7.3%

Behavior / access	%
Binge drinking	15.4%
No physical activity	36.5%
Less than 7 hrs sleep	35.1%
Fair or poor health	25.8%
Poor mental health	18.8%
Poor physical health	17.3%
No health insurance	21.5%
Visited doctor (checkup)	75.0%
Visited dentist	45.8%
Cholesterol screening	85.2%
Teeth loss	28.6%

Veterans & disability

Veterans	Count	%
Civilian veterans	220	5.4%

Disability	%
Any disability	31.3%
Under 18	11.9%
18–64 years	29.0%
65 and over	60.7%

Health insurance coverage

Type	%
Private insurance	42.4%
Public insurance	53.4%
Uninsured under 19	7.9%

Language & origin

Language spoken at home (age 5+)

Language	Count	%
English only	5,167	94.6%
Spanish	68	1.3%
Other Indo-European	59	1.1%
Asian & Pacific Islander	9	0.2%
Other languages	0	0.0%

Place of birth & citizenship

Origin	Count	%
Native born (US)	5,409	99.0%
Born in same state	5,409	99.0%
Born in different state	4,696	86.0%
Foreign born	0	0.0%
Naturalized citizen	54	1.0%
Not a US citizen	9	16.7%

Ancestry

Ancestry	Count	%
Arab	745	13.6%
French	701	12.8%
Italian	435	8%

Ancestry	Count	%
English	71	1.3%
Polish	11	0.2%

Technology access

Metric	% of households
Computer access	42.9%
Internet access	81.5%

Source: U.S. Census Bureau, American Community Survey 2025 estimates.

Frequently asked questions

What ZIP codes does East Prairie, MO have?

East Prairie, MO has one ZIP code: 63845. Each ZIP code serves a distinct delivery area within the city and surrounding region.