49221 ZIP Code — Adrian, MI

Lenawee County, Michigan

ZIP code 49221 is located in Adrian, Michigan, within Lenawee County. It covers approximately 119.88 square miles and serves a population of 41,209 residents. This is a standard ZIP code in the Eastern (ET) timezone, served by area code 517.

About ZIP code 49221

The housing stock consists of a mix of housing types. Most homes were built in the pre-1940, giving the area an established character. Median home value is $146,600. Owner-occupancy sits near the national average at 70%.

Median household income is $56,640. 38% of households receive Social Security income, suggesting a notable retiree or disability population.

The dominant occupation class is management, business, and professional, with education and healthcare as the leading industry. The average commute of 21 minutes is near the national average.

Educational attainment is near the national average, with 21% of residents holding a bachelor's degree or higher.

Health indicators show elevated rates of smoking (21%) compared to national benchmarks.

41,209

population

119.88

sq mi land

Standard

ZIP type

Eastern (ET)

timezone

49221 ZIP code map

Cities in ZIP code 49221

Below are the cities the US Postal Service accepts for ZIP code 49221. Using any city not on this list may result in mail delivery delays.

City	Status
Adrian	Acceptable
Adrian	Preferred

Nearby ZIP codes

49268 Palmyra (6.7 mi) 49235 Clayton (8.1 mi) 49279 Sand Creek (8.4 mi) 49248 Jasper (8.9 mi) 49265 Onsted (9.7 mi) 49287 Tipton (9.8 mi) 49286 Tecumseh (11 mi) 49228 Blissfield (11.6 mi) 49253 Manitou Beach (12.2 mi) 49256 Morenci (12.4 mi) 49238 Deerfield (13.4 mi) 49229 Britton (13.5 mi)

Demographics updated 06/2026

Population
Total population	41,209
Population density	344 / sq mi
State FIPS	26
County FIPS	091

Geography
Land area	119.88 sq mi
Water area	0.65 sq mi
Latitude	41.8935
Longitude	-84.0613
Timezone	Eastern (ET)
Area code	517

Total population by age

Gender

Race & ethnicity

Economics updated 06/2026

Household income

Income range	This ZIP	County avg	State avg
Under $50k	52.0%	44.1%	42.6%
$50k – $100k	31.7%	33.9%	31.1%
$100k – $200k	14.1%	18.9%	20.6%
Over $200k	2.2%	3.1%	5.7%

Demographics & statistics

41,209

Population

344

People per sq mi

39.6

Median age

$56,640

Median household income

$28,461

Per capita income

$146,600

Median home value

$932

Median monthly rent

70.2%

Home ownership

17.3%

Poverty rate

6.0%

Unemployment

12,260

Housing units

21.3%

Bachelor's or higher

Age distribution

Male Female

1,033

Under 5

954

1,237

5–9

1,143

1,244

10–14

1,149

1,496

15–19

1,382

1,816

20–24

1,676

2,509

25–34

2,317

2,626

35–44

2,425

2,798

45–54

2,583

1,102

55–59

1,018

1,467

60–64

1,355

2,277

65–74

2,102

1,208

75–84

1,115

612

85+

565

← Male

Female →

Age summary

Group	Count	%
Under 18	8,041	19.5%
18 and over	33,168	80.5%
65 and over	7,879	19.1%
Median age	39.6 years

Race & ethnicity

White 82.7%

Two or more races 6.5%

Hispanic or Latino 4.2%

Black or African American 4.1%

Other race 1.8%

American Indian / Alaska Native 0.4%

Asian 0.3%

Group	Count	%
White	35,557	82.7%
Two or more races	2,785	6.5%
Hispanic or Latino	1,808	4.2%
Black or African American	1,777	4.1%
Other race	783	1.8%
American Indian / Alaska Native	153	0.4%
Asian	136	0.3%

Household income

Income range	This ZIP	County avg	State avg
Under $50k	52.0%	44.1%	42.6%
$50k – $100k	31.7%	33.9%	31.1%
$100k – $200k	14.1%	18.9%	20.6%
Over $200k	2.2%	3.1%	5.7%

Under $10k 6.7%

$10k–$15k 3.7%

$15k–$25k 10.9%

$25k–$35k 9.9%

$35k–$50k 14.4%

$50k–$75k 19.6%

$75k–$100k 14.1%

$100k–$150k 11.9%

$150k–$200k 4.3%

$200k+ 4.4%

Range	% of households
Under $10k	6.7%
$10k–$15k	3.7%
$15k–$25k	10.9%
$25k–$35k	9.9%
$35k–$50k	14.4%
$50k–$75k	19.6%
$75k–$100k	14.1%
$100k–$150k	11.9%
$150k–$200k	4.3%
$200k+	4.4%
Median income	$56,640

Housing

Home values

Under $50k 14.2%

$50k–$100k 16.0%

$100k–$150k 21.7%

$150k–$200k 19.9%

$200k–$300k 21.2%

$300k–$500k 5.7%

$500k–$1M 1.1%

$1M+ 0.3%

Housing overview

Metric	Value
Median home value	$146,600
Median rent / month	$932
Owner occupied	70.2%
Renter occupied	29.8%
Vacant	8.5%
Single-family detached	67.2%
Large apartment buildings	5.3%
Mobile homes	8.3%
Median rooms	5.9
Avg household size (owned)	2.46

Year built

Era	%
2020 or later	0.0%
2010–2019	2.1%
2000–2009	11.9%
1990–1999	17.2%
1980–1989	7.4%
1970–1979	13.1%
1960–1969	9.9%
1950–1959	11.9%
1940–1949	6.4%
1939 or earlier	20.1%

Bedrooms

Size	% of units
No bedroom (studio)	1.3%
1 bedroom	10.5%
2 bedrooms	22.2%
3 bedrooms	46.1%
4 bedrooms	15.3%
5+ bedrooms	4.7%

Vehicles per household

Vehicles	% of households
No vehicle	7.3%
1 vehicle	33.7%
2 vehicles	43.0%
3 or more	16.1%

Heating fuel

Fuel type	%
Utility gas	88.4%
Electricity	6.5%
Propane / LP gas	2.8%
Fuel oil	0.4%
Wood	0.8%
No fuel used	0.6%

Households & families

Household type	Count	%
Married-couple family	6,598	42.8%
Cohabiting couple	1,522	9.9%
Male householder, no spouse	3,014	19.5%
Female householder, no spouse	4,287	27.8%
Households with children under 18	4,480	29.1%
Households with seniors (65+)	5,229	33.9%
Average household size	2.37

Marital status

Status	Male	Female
Never married	41.9%	32.2%
Married	40.1%	43.0%
Separated	1.6%	2.1%
Widowed	2.4%	9.2%
Divorced	14.1%	13.5%

Education

Less than 9th grade 3.3%

Some HS, no diploma 9.2%

HS graduate 37.7%

Some college, no degree 20.5%

Associate's degree 8.0%

Bachelor's degree 12.5%

Graduate / professional 8.8%

Metric	%
HS diploma or higher	87.4%
Bachelor's or higher	21.3%

School enrollment (ages 3–17)

Type	Count	%
Nursery / preschool	481	4.8%
Kindergarten	483	4.8%
Elementary school	3,624	36.2%
High school	1,892	18.9%
College / grad school	3,542	35.3%

Employment

Industry of employment

Education & healthcare 25.6%

Manufacturing 19.4%

Arts, food & hospitality 11.7%

Retail trade 11.1%

Professional & management 6.2%

Construction 5.8%

Other services 4.7%

Public administration 4.5%

Transportation & utilities 3.6%

Finance & real estate 2.5%

Wholesale trade 1.9%

Agriculture & mining 1.8%

Information 1.2%

Occupation

Category	%
Management, business & arts	29.1%
Service	23.4%
Sales & office	17.9%
Natural resources & construction	8.5%
Production & transportation	21.1%

Employment type

Type	%
Private sector	82.0%
Government	11.8%
Self-employed	6.1%
Unpaid family workers	0.1%

Commute

Method	%
Drive alone	78.3%
Carpool	8.4%
Public transit	0.2%
Walk	4.3%
Work from home	7.5%
Other means	1.3%
Avg commute (minutes)	20.7

Poverty

All people 17.3%

Under 18 years 23.0%

18 and over 15.7%

Married-couple families 7.5%

Female-led households 26.7%

Income support

Source	% of households
Social Security	37.8%
Retirement income	31.7%
Supplemental Security	7.8%
Cash public assistance	1.9%
Food stamps / SNAP	14.8%

Health indicators

Condition	%
Obesity	41.6%
High blood pressure	33.0%
High cholesterol	31.6%
Diabetes	11.5%
Heart disease	6.8%
Stroke	3.3%
Asthma	11.1%
Arthritis	28.7%
Kidney disease	3.0%
Pulmonary disease	8.0%
Cancer	6.5%

Behavior / access	%
Smoking	20.5%
Binge drinking	19.4%
No physical activity	24.2%
Less than 7 hrs sleep	35.9%
Depression	22.6%
Fair or poor health	16.5%
Poor mental health	17.2%
Poor physical health	11.7%
No health insurance	12.4%
Visited doctor (checkup)	72.4%
Visited dentist	62.8%
Cholesterol screening	89.2%
Teeth loss	15.3%

Veterans & disability

Veterans	Count	%
Civilian veterans	2,095	6.3%

Disability	%
Any disability	15.2%
Under 18	4.6%
18–64 years	13.3%
65 and over	32.9%

Health insurance coverage

Type	%
Private insurance	66.4%
Public insurance	44.9%
No insurance	6.8%
Uninsured under 19	3.7%

Language & origin

Language spoken at home (age 5+)

Language	Count	%
English only	39,222	95.2%
Spanish	1,361	3.5%
Other Indo-European	1,093	2.8%
Asian & Pacific Islander	34	0.1%
Other languages	21	0.1%

Place of birth & citizenship

Origin	Count	%
Native born (US)	39,795	96.6%
Born in same state	39,421	95.7%
Born in different state	30,270	73.5%
Foreign born	374	0.9%
Naturalized citizen	1,414	3.4%
Not a US citizen	541	38.3%

Ancestry

Ancestry	Count	%
Arab	5,912	14.3%
French	4,612	11.2%
Italian	4,254	10.3%
German	465	1.1%
Irish	446	1.1%

Ancestry	Count	%
English	419	1%
Polish	96	0.2%
Dutch	56	0.1%
Norwegian	5	0%

Technology access

Metric	% of households
Computer access	37.4%
Internet access	92.1%

Source: U.S. Census Bureau, American Community Survey 2025 estimates.

Frequently asked questions about ZIP code 49221

What city is ZIP code 49221 in?

ZIP code 49221 is primarily assigned to Adrian, Michigan.

What county is ZIP code 49221 in?

ZIP code 49221 falls within Lenawee County, Michigan.

What is the poverty rate in ZIP code 49221?

17% of residents in ZIP code 49221 live below the poverty line, above the national average.

Does ZIP code 49221 have a large retiree population?

38% of households in ZIP code 49221 receive Social Security income, suggesting a significant retiree or disability population.

What is the typical home value in ZIP code 49221?

The median home value in ZIP code 49221 is $146,600.

What is the population of ZIP code 49221?

ZIP code 49221 has an estimated population of 41,209 residents, with a density of 344 people per square mile.

What timezone is ZIP code 49221 in?

ZIP code 49221 observes the EST timezone.