Woodruff, SC is a city located in Spartanburg County, South Carolina and has a land area of 97.22 square miles (251.80 km2). The water area for the city is 0.70 square miles or 1.81 km2. There is one unique zip code in Woodruff, South Carolina and it is 29388. The area code(s) for Woodruff is 864.
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