Opelousas, LA is a city located in Saint Landry County, Louisiana and has a land area of 171.78 square miles (444.91 km2). The water area for the city is 0.55 square miles or 1.42 km2. There are 2 total unique zip codes in Opelousas, Louisiana. The area code(s) for Opelousas is 337.
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