Manistique, MI is a city located in Schoolcraft County, Michigan and has a land area of 473.93 square miles (1,227.47 km2). The water area for the city is 34.52 square miles or 89.41 km2. There is one unique zip code in Manistique, Michigan and it is 49854. The area code(s) for Manistique is 906.
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