Manderson, SD is a city located in Oglala Lakota County, South Dakota and has a land area of 66.42 square miles (172.03 km2). The water area for the city is 0.00 square miles or 0.00 km2. There is one unique zip code in Manderson, South Dakota and it is 57756. The area code(s) for Manderson is 605.
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