Madisonville, KY is a city located in Hopkins County, Kentucky and has a land area of 166.67 square miles (431.67 km2). The water area for the city is 6.35 square miles or 16.45 km2. There is one unique zip code in Madisonville, Kentucky and it is 42431. The area code(s) for Madisonville is 270/364.
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