There is one unique ZIP code in Lake City, South Carolina and it is 29560. Area code: 843/854.
1
ZIP codes
164.89
sq mi land
0.09
sq mi water
843/854
area code
Lake City, SC ZIP code map
About Lake City, SC
Lake City is a charming city located in the heart of South Carolina. As the county seat of Florence County, it serves as a hub for local commerce and community activities. With its rich history and friendly atmosphere, Lake City attracts both residents and visitors alike.
Location & geography
Lake City is situated in Florence County, approximately 20 miles west of the larger city of Florence and about 50 miles east of Columbia, the state capital. The city covers a land area of 164.89 square miles, with a minimal water area of 0.09 square miles. This flat terrain is characteristic of much of the surrounding area, offering scenic views of the natural landscapes of South Carolina.
Community & economy
The community of Lake City boasts a small-town charm with a strong sense of belonging among its residents. Its economy is supported by agriculture, manufacturing, and retail, contributing to a balanced lifestyle for those who call it home. Daily life in Lake City is enriched by local events and gatherings that foster community spirit.
Transportation
Lake City is conveniently accessed via U.S. Highway 52, which runs north-south and connects to other major roads in the region. The nearest airport is Florence Regional Airport, located roughly 25 miles to the east, providing additional connectivity for residents and visitors. Public transit options may be limited, so personal vehicles are the primary mode of transportation.
History
Lake City was founded in the mid-19th century and has since evolved into a center for agriculture and commerce. Notable events in its history include the establishment of numerous cotton and tobacco farms that helped shape the local economy. Today, the city honors its agricultural roots while embracing modern growth and development.
Did you know?
One surprising fact about Lake City is that it hosts the annual ArtFields festival, which celebrates Southern art and brings thousands of visitors to the region. This event showcases local and national artists, positioning Lake City as a cultural hotspot within South Carolina.
Source: U.S. Census Bureau, American Community Survey 2025 estimates.
Frequently asked questions
What is the ZIP code for Lake City, SC?
Lake City, SC has one ZIP code: 29560.
What is the main ZIP code for Lake City, SC?
The primary ZIP code for Lake City, SC is 29560. The city uses area code 843 or 854 for phone service.
What county is Lake City, SC in?
Lake City is located in Florence County, South Carolina.
How many ZIP codes are in Lake City, SC?
Lake City, SC has 1 ZIP code.
What ZIP code covers the downtown Lake City area and the historic Main Street district?
The downtown Lake City area, including the Main Street district, is located in ZIP code 29560, which serves as the primary commercial and civic center of the city.
What is the ZIP code for Lake City High School and the surrounding educational facilities in Lake City?
Lake City High School and other educational institutions in Lake City are located in ZIP code 29560, which encompasses the city's main populated areas and public facilities.
Need the complete South Carolina ZIP code database?Download all SC ZIP codes — Excel, CSV, or Access. Includes lat/lng, county FIPS & timezone.