Guayanilla, PR is a city located in Guayanilla County, Puerto Rico and has a land area of 42.14 square miles (109.14 km2). The water area for the city is 4.05 square miles or 10.49 km2. There is one unique zip code in Guayanilla, Puerto Rico and it is 00656. The area code(s) for Guayanilla is 787.
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