There is one unique ZIP code in Florence, Mississippi and it is 39073. Area code: 601.
1
ZIP codes
161.10
sq mi land
0.93
sq mi water
601
area code
Florence, MS ZIP code map
About Florence, MS
Florence, Mississippi is a small, growing community located in Rankin County, one of the fastest-developing counties in the state. Served by a single ZIP code — 39073 — Florence offers residents a quiet, suburban lifestyle with convenient access to the amenities of larger neighboring cities. The town has become increasingly attractive to families and professionals seeking affordable housing and a strong sense of community in central Mississippi.
Location & geography
Florence is situated in Rankin County in central Mississippi, positioned roughly between the state capital of Jackson to the northwest and Richland to the north. The city covers a total land area of 161.10 square miles, making it a geographically expansive community, complemented by 0.93 square miles of water area from local creeks and small water bodies. The terrain is characteristic of the Mississippi Piney Woods region, featuring gently rolling hills, mixed pine and hardwood forests, and fertile lowlands.
Community & economy
Florence has the feel of a close-knit, small-town community where neighbors know each other and local events bring residents together throughout the year. The local economy is supported by a mix of retail businesses, light industry, agriculture, and residents who commute to jobs in the greater Jackson metropolitan area. Daily life in Florence centers around its schools, churches, local eateries, and family-friendly neighborhoods that continue to attract new residents drawn by the area's affordability and charm.
Transportation
Florence is primarily accessed via U.S. Highway 49, which serves as a major north-south corridor connecting the community to Jackson to the north and Hattiesburg to the south. State Highway 469 also passes through the area, providing additional connectivity to neighboring communities in Rankin County. The nearest commercial airport is Jackson-Medgar Wiley Evers International Airport, located approximately 15 to 20 miles northwest of Florence, offering regional and national flight connections.
History
Florence was established as a rural agricultural community in Rankin County during the nineteenth century, with farming — particularly cotton — serving as the backbone of the local economy for generations. Over the decades, the town evolved from a purely agricultural settlement into a bedroom community as the Jackson metropolitan area expanded and infrastructure improved throughout central Mississippi. The growth of U.S. Highway 49 as a major transportation artery helped spur gradual residential and commercial development that has continued into the twenty-first century.
Did you know?
Despite its relatively modest size and population, Florence sits within one of the top-growing counties in Mississippi, making it a quiet front-row seat to some of the state's most dynamic suburban expansion. Florence's ZIP code, 39073, encompasses a remarkably large land area of over 161 square miles, meaning the community's footprint rivals that of many much larger cities across the country.
Source: U.S. Census Bureau, American Community Survey 2025 estimates.
Frequently asked questions
What is the ZIP code for Florence, MS?
Florence, MS has one ZIP code: 39073.
What is the main ZIP code for Florence, MS?
The primary ZIP code for Florence, MS is 39073. The city uses area code 601 for phone service.
What county is Florence, MS in?
Florence is located in Rankin County, Mississippi.
How many ZIP codes are in Florence, MS?
Florence, MS has 1 ZIP code.
What ZIP code should I use when mailing a letter to a business in downtown Florence, MS?
Downtown Florence is located in ZIP code 39073, which serves the central business district and historic downtown area of Florence in Rankin County.
If I'm sending a package to Florence High School in Florence, MS, what ZIP code do I need?
Florence High School is located in Florence, MS 39073, which is the sole ZIP code serving all areas of the city including its schools and public institutions.
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