De Smet, SD is a city located in Kingsbury County, South Dakota and has a land area of 249.28 square miles (645.63 km2). The water area for the city is 12.85 square miles or 33.28 km2. There is one unique zip code in De Smet, South Dakota and it is 57231. The area code(s) for De Smet is 605.
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