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Indiana ZIP Codes
Marion County
Indianapolis, IN
46221
46221 ZIP Code — Indianapolis, IN
Marion County, Indiana
ZIP code 46221 is located in
Indianapolis ,
Indiana ,
within Marion County .
It covers approximately 19.98 square miles and serves a population of
27,038 residents.
This is a standard ZIP code in the Eastern (ET) timezone,
served by area code 317 .
About ZIP code 46221
The housing stock consists of predominantly single-family detached homes. Most homes were built in the 2000s, giving the area an established character. Median home value is $156,200. Owner-occupancy sits near the national average at 60%.
Median household income is $57,379. SNAP benefit usage at 17% of households reflects economic stress in the area.
The dominant occupation class is management, business, and professional, with education and healthcare as the leading industry. The average commute of 24 minutes is near the national average.
College attainment at 15% is below the national average, consistent with a trades and production-oriented local economy.
Health indicators show elevated rates of smoking (28%) compared to national benchmarks.
Overall, ZIP code 46221 reflects a community defined by a trades-oriented workforce and elevated reliance on food assistance.
46221 ZIP code map
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Cities in ZIP code 46221
Below are the cities the US Postal Service accepts for ZIP code 46221. Using any city not on this list may result in mail delivery delays.
Nearby ZIP codes
Demographics
updated 05/2026
Population
Total population
27,038
Population density
1,353 / sq mi
State FIPS
18
County FIPS
097
Geography
Land area
19.98 sq mi
Water area
0.33 sq mi
Latitude
39.6986
Longitude
-86.2351
Timezone
Eastern (ET)
Area code
317
Economics
updated 05/2026
Household income
Income range
This ZIP
County avg
State avg
Under $50k
50.5%
48.4%
42.9%
$50k – $100k
32.9%
29.9%
32.7%
$100k – $200k
16.0%
17.1%
19.8%
Over $200k
0.6%
4.6%
4.5%
Demographics & statistics
$57,379
Median household income
$156,200
Median home value
$1,109
Median monthly rent
14.9%
Bachelor's or higher
Age distribution
Age summary
Group Count %
Under 18 6,578 24.3%
18 and over 20,460 75.7%
65 and over 2,997 11.1%
Median age 34.4 years
Race & ethnicity
Black or African American
13.6%
American Indian / Alaska Native
0.1%
Group Count %
White 20,207 70.4%
Black or African American 3,899 13.6%
Hispanic or Latino 1,663 5.8%
Two or more races 1,649 5.7%
Other race 1,090 3.8%
Asian 155 0.5%
American Indian / Alaska Native 38 0.1%
Household income
Income range
This ZIP
County avg
State avg
Under $50k
50.5%
48.4%
42.9%
$50k – $100k
32.9%
29.9%
32.7%
$100k – $200k
16.0%
17.1%
19.8%
Over $200k
0.6%
4.6%
4.5%
Range % of households
Under $10k 4.3%
$10k–$15k 3.0%
$15k–$25k 5.3%
$25k–$35k 13.6%
$35k–$50k 20.3%
$50k–$75k 14.8%
$75k–$100k 14.5%
$100k–$150k 17.9%
$150k–$200k 4.6%
$200k+ 1.7%
Median income $57,379
Housing
Housing overview
Metric Value
Median home value $156,200
Median rent / month $1,109
Owner occupied 60.0%
Renter occupied 40.0%
Vacant 8.5%
Single-family detached 75.1%
Large apartment buildings 1.8%
Mobile homes 1.4%
Median rooms 5.6
Avg household size (owned) 2.75
Year built
Era %
2020 or later 0.0%
2010–2019 10.2%
2000–2009 17.3%
1990–1999 9.4%
1980–1989 8.9%
1970–1979 11.1%
1960–1969 9.9%
1950–1959 10.8%
1940–1949 6.2%
1939 or earlier 16.2%
Bedrooms
Size % of units
No bedroom (studio) 0.4%
1 bedroom 11.8%
2 bedrooms 23.1%
3 bedrooms 50.4%
4 bedrooms 12.7%
5+ bedrooms 1.6%
Vehicles per household
Vehicles % of households
No vehicle 9.7%
1 vehicle 30.2%
2 vehicles 41.0%
3 or more 19.1%
Heating fuel
Fuel type %
Utility gas 51.0%
Electricity 46.6%
Propane / LP gas 1.2%
Fuel oil 0.7%
No fuel used 0.3%
Households & families
Household type Count %
Married-couple family 4,320 41.3%
Cohabiting couple 1,160 11.1%
Male householder, no spouse 1,999 19.1%
Female householder, no spouse 2,984 28.5%
Households with children under 18 2,943 28.1%
Households with seniors (65+) 2,221 21.2%
Average household size 2.58
Marital status
Status Male Female
Never married 38.5% 35.4%
Married 43.7% 42.8%
Separated 2.1% 1.8%
Widowed 2.4% 8.0%
Divorced 13.4% 12.0%
Education
Some college, no degree
19.8%
Graduate / professional
4.0%
Metric %
HS diploma or higher 83.4%
Bachelor's or higher 14.9%
School enrollment (ages 3–17)
Type Count %
Nursery / preschool 302 5.3%
Kindergarten 274 4.8%
Elementary school 3,121 54.6%
High school 1,060 18.6%
College / grad school 956 16.7%
Employment
Industry of employment
Education & healthcare
15.9%
Transportation & utilities
15.1%
Professional & management
10.5%
Arts, food & hospitality
5.8%
Public administration
5.3%
Finance & real estate
4.8%
Agriculture & mining
0.7%
Occupation
Category %
Management, business & arts 26.3%
Service 17.6%
Sales & office 19.1%
Natural resources & construction 10.7%
Production & transportation 26.3%
Employment type
Type %
Private sector 84.4%
Government 12.8%
Self-employed 2.6%
Unpaid family workers 0.1%
Commute
Method %
Drive alone 81.6%
Carpool 10.1%
Public transit 0.5%
Walk 1.2%
Work from home 4.9%
Other means 1.8%
Avg commute (minutes) 24.3
Poverty
Married-couple families
4.6%
Female-led households
15.5%
Income support
Source % of households
Social Security 24.6%
Retirement income 19.5%
Supplemental Security 4.2%
Cash public assistance 3.1%
Food stamps / SNAP 17.2%
Health indicators
Condition %
Obesity 37.6%
High blood pressure 33.6%
High cholesterol 32.1%
Diabetes 11.0%
Heart disease 6.9%
Stroke 3.3%
Asthma 11.3%
Arthritis 23.6%
Kidney disease 3.1%
Pulmonary disease 9.7%
Cancer 5.5%
Behavior / access %
Smoking 27.8%
Binge drinking 19.1%
No physical activity 30.9%
Less than 7 hrs sleep 36.9%
Depression 26.8%
Fair or poor health 19.6%
Poor mental health 18.5%
Poor physical health 13.3%
No health insurance 17.1%
Visited doctor (checkup) 70.7%
Visited dentist 55.7%
Cholesterol screening 85.0%
Teeth loss 23.7%
Veterans & disability
Veterans Count %
Civilian veterans 1,577 7.7%
Disability %
Any disability 16.6%
Under 18 9.4%
18–64 years 15.7%
65 and over 38.3%
Health insurance coverage
Type %
Private insurance 61.8%
Public insurance 41.2%
No insurance 7.1%
Uninsured under 19 5.8%
Language & origin
Language spoken at home (age 5+)
Language Count %
English only 25,030 92.6%
Spanish 1,104 4.4%
Other Indo-European 794 3.2%
Asian & Pacific Islander 39 0.2%
Other languages 67 0.3%
Place of birth & citizenship
Origin Count %
Native born (US) 25,372 93.8%
Born in same state 25,048 92.6%
Born in different state 18,240 67.5%
Foreign born 324 1.2%
Naturalized citizen 1,666 6.2%
Not a US citizen 620 37.2%
Ancestry
Ancestry Count %
French 2,785 10.3%
Arab 2,668 9.9%
Italian 2,497 9.2%
English 433 1.6%
Ancestry Count %
Polish 200 0.7%
Dutch 105 0.4%
Irish 7 0%
Technology access
Metric % of households
Computer access 38.7%
Internet access 94.4%
Source: U.S. Census Bureau, American Community Survey 2025 estimates.
Frequently asked questions about ZIP code 46221
What city is ZIP code 46221 in?
ZIP code 46221 is primarily assigned to Indianapolis, Indiana.
What county is ZIP code 46221 in?
ZIP code 46221 falls within Marion County, Indiana.
How educated is the population of ZIP code 46221?
15% of residents hold a bachelor's degree or higher — below the national average of ~33%, consistent with a trades-oriented local economy.
What is the typical home value in ZIP code 46221?
The median home value in ZIP code 46221 is $156,200.
What is the population of ZIP code 46221?
ZIP code 46221 has an estimated population of 27,038 residents, with a density of 1,353 people per square mile.
What is the median household income in ZIP code 46221?
The median household income in ZIP code 46221 is $57,379, below the national median of ~$75,000.
What timezone is ZIP code 46221 in?
ZIP code 46221 observes the EST timezone.
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