46221 ZIP Code — Indianapolis, IN

Marion County, Indiana

ZIP code 46221 is located in Indianapolis, Indiana, within Marion County. It covers approximately 19.98 square miles and serves a population of 27,038 residents. This is a standard ZIP code in the Eastern (ET) timezone, served by area code 317.

About ZIP code 46221

The housing stock consists of predominantly single-family detached homes. Most homes were built in the 2000s, giving the area an established character. Median home value is $156,200. Owner-occupancy sits near the national average at 60%.

Median household income is $57,379. SNAP benefit usage at 17% of households reflects economic stress in the area.

The dominant occupation class is management, business, and professional, with education and healthcare as the leading industry. The average commute of 24 minutes is near the national average.

College attainment at 15% is below the national average, consistent with a trades and production-oriented local economy.

Health indicators show elevated rates of smoking (28%) compared to national benchmarks.

Overall, ZIP code 46221 reflects a community defined by a trades-oriented workforce and elevated reliance on food assistance.

27,038
population
19.98
sq mi land
Standard
ZIP type
Eastern (ET)
timezone
46221 ZIP code map
Cities in ZIP code 46221

Below are the cities the US Postal Service accepts for ZIP code 46221. Using any city not on this list may result in mail delivery delays.

City Status
Indianapolis Acceptable
Indianapolis Preferred
Nearby ZIP codes
46241 Indianapolis (1.9 mi) 46217 Indianapolis (2.4 mi) 46225 Indianapolis (4.7 mi) 46231 Indianapolis (5 mi) 46227 Indianapolis (5.9 mi) 46113 Camby (6 mi) 46209 Indianapolis (6.3 mi) 46285 Indianapolis (6.3 mi) 46283 Indianapolis (6.3 mi) 46277 Indianapolis (6.3 mi) 46255 Indianapolis (6.3 mi) 46249 Indianapolis (6.3 mi)
Demographics updated 05/2026
Population
Total population 27,038
Population density 1,353 / sq mi
State FIPS 18
County FIPS 097
Geography
Land area 19.98 sq mi
Water area 0.33 sq mi
Latitude 39.6986
Longitude -86.2351
Timezone Eastern (ET)
Area code 317
Total population by age
Gender
Race & ethnicity
Economics updated 05/2026
Household income
Income range This ZIP County avg State avg
Under $50k 50.5% 48.4% 42.9%
$50k – $100k 32.9% 29.9% 32.7%
$100k – $200k 16.0% 17.1% 19.8%
Over $200k 0.6% 4.6% 4.5%

Demographics & statistics

27,038
Population
1,353
People per sq mi
34.4
Median age
$57,379
Median household income
$30,375
Per capita income
$156,200
Median home value
$1,109
Median monthly rent
60.0%
Home ownership
12.1%
Poverty rate
5.8%
Unemployment
7,246
Housing units
14.9%
Bachelor's or higher

Age distribution

Male Female
1,015
Under 5
993
942
5–9
921
933
10–14
912
655
15–19
641
1,163
20–24
1,136
2,261
25–34
2,211
1,552
35–44
1,518
1,988
45–54
1,943
943
55–59
922
704
60–64
688
1,028
65–74
1,005
345
75–84
337
143
85+
139
← Male
Female →

Age summary

GroupCount%
Under 186,57824.3%
18 and over20,46075.7%
65 and over2,99711.1%
Median age34.4 years

Race & ethnicity

White 70.4%
Black or African American 13.6%
Hispanic or Latino 5.8%
Two or more races 5.7%
Other race 3.8%
Asian 0.5%
American Indian / Alaska Native 0.1%
GroupCount%
White20,20770.4%
Black or African American3,89913.6%
Hispanic or Latino1,6635.8%
Two or more races1,6495.7%
Other race1,0903.8%
Asian1550.5%
American Indian / Alaska Native380.1%

Household income

Income range This ZIP County avg State avg
Under $50k 50.5% 48.4% 42.9%
$50k – $100k 32.9% 29.9% 32.7%
$100k – $200k 16.0% 17.1% 19.8%
Over $200k 0.6% 4.6% 4.5%
Under $10k 4.3%
$10k–$15k 3.0%
$15k–$25k 5.3%
$25k–$35k 13.6%
$35k–$50k 20.3%
$50k–$75k 14.8%
$75k–$100k 14.5%
$100k–$150k 17.9%
$150k–$200k 4.6%
$200k+ 1.7%
Range% of households
Under $10k4.3%
$10k–$15k3.0%
$15k–$25k5.3%
$25k–$35k13.6%
$35k–$50k20.3%
$50k–$75k14.8%
$75k–$100k14.5%
$100k–$150k17.9%
$150k–$200k4.6%
$200k+1.7%
Median income$57,379

Housing

Home values

Under $50k 5.3%
$50k–$100k 17.6%
$100k–$150k 22.9%
$150k–$200k 31.4%
$200k–$300k 20.4%
$300k–$500k 1.7%
$500k–$1M 0.4%
$1M+ 0.3%

Housing overview

MetricValue
Median home value$156,200
Median rent / month$1,109
Owner occupied60.0%
Renter occupied40.0%
Vacant8.5%
Single-family detached75.1%
Large apartment buildings1.8%
Mobile homes1.4%
Median rooms5.6
Avg household size (owned)2.75

Year built

Era%
2020 or later0.0%
2010–201910.2%
2000–200917.3%
1990–19999.4%
1980–19898.9%
1970–197911.1%
1960–19699.9%
1950–195910.8%
1940–19496.2%
1939 or earlier16.2%

Bedrooms

Size% of units
No bedroom (studio)0.4%
1 bedroom11.8%
2 bedrooms23.1%
3 bedrooms50.4%
4 bedrooms12.7%
5+ bedrooms1.6%

Vehicles per household

Vehicles% of households
No vehicle9.7%
1 vehicle30.2%
2 vehicles41.0%
3 or more19.1%

Heating fuel

Fuel type%
Utility gas51.0%
Electricity46.6%
Propane / LP gas1.2%
Fuel oil0.7%
No fuel used0.3%

Households & families

Household typeCount%
Married-couple family4,32041.3%
Cohabiting couple1,16011.1%
Male householder, no spouse1,99919.1%
Female householder, no spouse2,98428.5%
Households with children under 182,94328.1%
Households with seniors (65+)2,22121.2%
Average household size2.58

Marital status

StatusMaleFemale
Never married38.5%35.4%
Married43.7%42.8%
Separated2.1%1.8%
Widowed2.4%8.0%
Divorced13.4%12.0%

Education

Less than 9th grade 6.9%
Some HS, no diploma 9.7%
HS graduate 38.4%
Some college, no degree 19.8%
Associate's degree 10.4%
Bachelor's degree 10.9%
Graduate / professional 4.0%
Metric%
HS diploma or higher83.4%
Bachelor's or higher14.9%

School enrollment (ages 3–17)

TypeCount%
Nursery / preschool3025.3%
Kindergarten2744.8%
Elementary school3,12154.6%
High school1,06018.6%
College / grad school95616.7%

Employment

Industry of employment

Education & healthcare 15.9%
Transportation & utilities 15.1%
Manufacturing 13.9%
Retail trade 11.0%
Professional & management 10.5%
Construction 8.4%
Arts, food & hospitality 5.8%
Public administration 5.3%
Finance & real estate 4.8%
Other services 4.6%
Wholesale trade 3.0%
Information 0.9%
Agriculture & mining 0.7%

Occupation

Category%
Management, business & arts26.3%
Service17.6%
Sales & office19.1%
Natural resources & construction10.7%
Production & transportation26.3%

Employment type

Type%
Private sector84.4%
Government12.8%
Self-employed2.6%
Unpaid family workers0.1%

Commute

Method%
Drive alone81.6%
Carpool10.1%
Public transit0.5%
Walk1.2%
Work from home4.9%
Other means1.8%
Avg commute (minutes)24.3

Poverty

All people 12.1%
Under 18 years 17.1%
18 and over 10.6%
Married-couple families 4.6%
Female-led households 15.5%

Income support

Source% of households
Social Security24.6%
Retirement income19.5%
Supplemental Security4.2%
Cash public assistance3.1%
Food stamps / SNAP17.2%

Health indicators

Condition%
Obesity37.6%
High blood pressure33.6%
High cholesterol32.1%
Diabetes11.0%
Heart disease6.9%
Stroke3.3%
Asthma11.3%
Arthritis23.6%
Kidney disease3.1%
Pulmonary disease9.7%
Cancer5.5%
Behavior / access%
Smoking27.8%
Binge drinking19.1%
No physical activity30.9%
Less than 7 hrs sleep36.9%
Depression26.8%
Fair or poor health19.6%
Poor mental health18.5%
Poor physical health13.3%
No health insurance17.1%
Visited doctor (checkup)70.7%
Visited dentist55.7%
Cholesterol screening85.0%
Teeth loss23.7%

Veterans & disability

VeteransCount%
Civilian veterans1,5777.7%
Disability%
Any disability16.6%
Under 189.4%
18–64 years15.7%
65 and over38.3%

Health insurance coverage

Type%
Private insurance61.8%
Public insurance41.2%
No insurance7.1%
Uninsured under 195.8%

Language & origin

Language spoken at home (age 5+)

LanguageCount%
English only25,03092.6%
Spanish1,1044.4%
Other Indo-European7943.2%
Asian & Pacific Islander390.2%
Other languages670.3%

Place of birth & citizenship

OriginCount%
Native born (US)25,37293.8%
Born in same state25,04892.6%
Born in different state18,24067.5%
Foreign born3241.2%
Naturalized citizen1,6666.2%
Not a US citizen62037.2%

Ancestry

AncestryCount%
French2,78510.3%
Arab2,6689.9%
Italian2,4979.2%
English4331.6%
AncestryCount%
Polish2000.7%
Dutch1050.4%
Irish70%

Technology access

Metric% of households
Computer access38.7%
Internet access94.4%

Source: U.S. Census Bureau, American Community Survey 2025 estimates.

Frequently asked questions about ZIP code 46221

What city is ZIP code 46221 in?

ZIP code 46221 is primarily assigned to Indianapolis, Indiana.

What county is ZIP code 46221 in?

ZIP code 46221 falls within Marion County, Indiana.

How educated is the population of ZIP code 46221?

15% of residents hold a bachelor's degree or higher — below the national average of ~33%, consistent with a trades-oriented local economy.

What is the typical home value in ZIP code 46221?

The median home value in ZIP code 46221 is $156,200.

What is the population of ZIP code 46221?

ZIP code 46221 has an estimated population of 27,038 residents, with a density of 1,353 people per square mile.

What is the median household income in ZIP code 46221?

The median household income in ZIP code 46221 is $57,379, below the national median of ~$75,000.

What timezone is ZIP code 46221 in?

ZIP code 46221 observes the EST timezone.

Need the complete ZIP code database? Download all 42,000+ US ZIP codes — Excel, CSV, or Access. Includes lat/lng, county FIPS & timezone.
Download database →