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Missouri ZIP Codes
Andrew County
Amazonia, MO
64421
64421 ZIP Code — Amazonia, MO
Andrew County, Missouri
ZIP code 64421 is located in
Amazonia ,
Missouri ,
within Andrew County .
It covers approximately 24.50 square miles and serves a population of
933 residents.
This is a standard ZIP code in the Central (CT) timezone,
served by area code 816 .
About ZIP code 64421
The housing stock consists of predominantly single-family detached homes. Most homes were built in the 1990s, giving the area an established character. Median home value is $104,200. Owner-occupancy is high at 86%, well above the national average.
Median household income is $70,125. SNAP benefit usage at 20% of households reflects economic stress in the area. 34% of households receive Social Security income, suggesting a notable retiree or disability population.
The dominant occupation class is production, transportation, and material moving, with manufacturing as the leading industry. The average commute of 25 minutes is near the national average.
College attainment at 4% is below the national average, consistent with a trades and production-oriented local economy.
Health indicators show elevated rates of smoking (24%) compared to national benchmarks.
Notable community characteristics include disability rates above the national average at 23%.
Overall, ZIP code 64421 reflects a community defined by a trades-oriented workforce, high homeownership, a significant Social Security-dependent population, and elevated reliance on food assistance.
64421 ZIP code map
View map of 64421
Cities in ZIP code 64421
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Nearby ZIP codes
Demographics
updated 05/2026
Population
Total population
933
Population density
38 / sq mi
State FIPS
29
County FIPS
003
Geography
Land area
24.50 sq mi
Water area
0.66 sq mi
Latitude
39.8981
Longitude
-94.9341
Timezone
Central (CT)
Area code
816
Economics
updated 05/2026
Household income
Income range
This ZIP
County avg
State avg
Under $50k
49.0%
44.0%
43.8%
$50k – $100k
36.8%
35.7%
31.5%
$100k – $200k
12.4%
18.3%
19.5%
Over $200k
1.7%
2.0%
5.2%
Demographics & statistics
$70,125
Median household income
$104,200
Median home value
$1,304
Median monthly rent
Age distribution
Age summary
Group Count %
Under 18 205 22.0%
18 and over 728 78.0%
65 and over 118 12.6%
Median age 46.3 years
Race & ethnicity
American Indian / Alaska Native
0.4%
Group Count %
White 905 94.6%
Hispanic or Latino 24 2.5%
Two or more races 24 2.5%
American Indian / Alaska Native 4 0.4%
Household income
Income range
This ZIP
County avg
State avg
Under $50k
49.0%
44.0%
43.8%
$50k – $100k
36.8%
35.7%
31.5%
$100k – $200k
12.4%
18.3%
19.5%
Over $200k
1.7%
2.0%
5.2%
Range % of households
Under $10k 16.7%
$10k–$15k 1.8%
$15k–$25k 10.4%
$25k–$35k 4.2%
$35k–$50k 6.6%
$50k–$75k 14.6%
$75k–$100k 19.7%
$100k–$150k 18.2%
$150k–$200k 4.8%
$200k+ 3.0%
Median income $70,125
Housing
Housing overview
Metric Value
Median home value $104,200
Median rent / month $1,304
Owner occupied 85.7%
Renter occupied 14.3%
Vacant 21.2%
Single-family detached 75.3%
Large apartment buildings 0.0%
Mobile homes 24.7%
Median rooms 5.5
Avg household size (owned) 2.87
Year built
Era %
2020 or later 0.2%
2010–2019 9.2%
2000–2009 20.7%
1990–1999 22.8%
1980–1989 16.2%
1970–1979 4.5%
1960–1969 11.3%
1950–1959 0.9%
1940–1949 1.4%
1939 or earlier 12.7%
Bedrooms
Size % of units
No bedroom (studio) 0.2%
1 bedroom 15.1%
2 bedrooms 27.3%
3 bedrooms 33.6%
4 bedrooms 21.4%
5+ bedrooms 2.4%
Vehicles per household
Vehicles % of households
No vehicle 0.3%
1 vehicle 12.2%
2 vehicles 55.2%
3 or more 32.2%
Heating fuel
Fuel type %
Utility gas 2.7%
Electricity 41.2%
Propane / LP gas 20.0%
Wood 3.9%
No fuel used 1.8%
Households & families
Household type Count %
Married-couple family 200 59.7%
Cohabiting couple 33 9.9%
Male householder, no spouse 32 9.6%
Female householder, no spouse 70 20.9%
Households with children under 18 85 25.4%
Households with seniors (65+) 95 28.4%
Average household size 2.79
Marital status
Status Male Female
Never married 20.8% 19.0%
Married 64.8% 46.9%
Separated 2.7% 2.7%
Widowed 3.3% 11.2%
Divorced 8.5% 20.2%
Education
Some college, no degree
23.4%
Graduate / professional
0.0%
Metric %
HS diploma or higher 89.2%
Bachelor's or higher 3.9%
School enrollment (ages 3–17)
Type Count %
Nursery / preschool 16 8.4%
Kindergarten 25 13.2%
Elementary school 64 33.7%
High school 41 21.6%
College / grad school 44 23.2%
Employment
Industry of employment
Education & healthcare
22.3%
Arts, food & hospitality
8.4%
Professional & management
5.7%
Finance & real estate
3.2%
Transportation & utilities
2.3%
Agriculture & mining
1.8%
Public administration
1.6%
Occupation
Category %
Management, business & arts 16.2%
Service 17.1%
Sales & office 19.4%
Natural resources & construction 11.8%
Production & transportation 35.5%
Employment type
Type %
Private sector 88.8%
Government 10.7%
Self-employed 0.5%
Unpaid family workers 0.0%
Commute
Method %
Drive alone 84.9%
Carpool 14.6%
Public transit 0.0%
Walk 0.2%
Work from home 0.2%
Other means 0.0%
Avg commute (minutes) 25.2
Poverty
Married-couple families
13.5%
Female-led households
13.6%
Income support
Source % of households
Social Security 34.0%
Retirement income 35.2%
Supplemental Security 2.4%
Cash public assistance 20.6%
Food stamps / SNAP 20.3%
Health indicators
Condition %
Obesity 40.8%
High blood pressure 32.8%
High cholesterol 34.8%
Diabetes 10.6%
Heart disease 7.4%
Stroke 3.4%
Asthma 9.7%
Arthritis 29.2%
Kidney disease 2.9%
Pulmonary disease 9.1%
Cancer 6.5%
Behavior / access %
Smoking 23.7%
Binge drinking 17.4%
No physical activity 29.0%
Less than 7 hrs sleep 33.2%
Depression 25.0%
Fair or poor health 17.7%
Poor mental health 16.3%
Poor physical health 12.7%
No health insurance 17.0%
Visited doctor (checkup) 72.6%
Visited dentist 56.1%
Cholesterol screening 87.0%
Teeth loss 20.3%
Veterans & disability
Veterans Count %
Civilian veterans 46 6.3%
Disability %
Any disability 23.2%
Under 18 9.3%
18–64 years 23.1%
65 and over 47.5%
Health insurance coverage
Type %
Private insurance 71.4%
Public insurance 36.4%
No insurance 8.8%
Uninsured under 19 5.9%
Language & origin
Language spoken at home (age 5+)
Language Count %
English only 869 93.1%
Spanish 0 0.0%
Other Indo-European 0 0.0%
Asian & Pacific Islander 0 0.0%
Other languages 0 0.0%
Place of birth & citizenship
Origin Count %
Native born (US) 933 100.0%
Born in same state 933 100.0%
Born in different state 780 83.6%
Foreign born 0 0.0%
Naturalized citizen 0 0.0%
Not a US citizen 0 0.0%
Ancestry
Ancestry Count %
French 145 15.5%
Italian 97 10.4%
Arab 27 2.9%
Ancestry Count %
Dutch 10 1.1%
English 3 0.3%
Technology access
Metric % of households
Computer access 35.9%
Internet access 87.2%
Source: U.S. Census Bureau, American Community Survey 2025 estimates.
Frequently asked questions about ZIP code 64421
What city is ZIP code 64421 in?
ZIP code 64421 is primarily assigned to Amazonia, Missouri.
What county is ZIP code 64421 in?
ZIP code 64421 falls within Andrew County, Missouri.
How educated is the population of ZIP code 64421?
4% of residents hold a bachelor's degree or higher — below the national average of ~33%, consistent with a trades-oriented local economy.
Is ZIP code 64421 mostly owner-occupied?
86% of occupied units in ZIP code 64421 are owner-occupied, well above the national average.
What is the typical home value in ZIP code 64421?
The median home value in ZIP code 64421 is $104,200.
What is the population of ZIP code 64421?
ZIP code 64421 has an estimated population of 933 residents, with a density of 38 people per square mile.
What timezone is ZIP code 64421 in?
ZIP code 64421 observes the CST timezone.
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